WHAT IS DONAMEM 5MG

 



DONAMEM 5MG is a combination of Donepezil and Memantine which belongs to the group of medicines called Acetylcholinesterase inhibitors and NMDA receptor antagonists respectively. It is used to treat moderate to severe dementia caused due to Alzheimer’s disease (Alzheimer’s type dementia) in patients previously treated with donepezil alone. Alzheimer’s type dementia is a type of brain disease where the dementia (disorder of thoughts, memory, and behaviour) happens due to degeneration of brain cells that carry memories.Donepezil is an acetylcholinesterase inhibitor. It acts by restoring the levels of a brain chemical called acetylcholine that carries messages within the nerve cells. Memantine is a NMDA receptor antagonist. It acts by suppressing the overactivation of certain brain chemicals (glutamate) that damages the nerve cells. Together, they help in reducing the symptoms of Alzheimer’s type dementia.

Before taking DONAMEM5MG inform your doctor if you have any liver, kidney, or heart problems. You must also inform your doctor if you have any stomach problems (ulcer or bleeding in the gut), breathing problems (asthma), bladder problems, epilepsy or are severely dehydrated due to excessive sweating, vomiting or diarrhea.

USES OF DONAMEM 5MG

Treats moderate to severe Alzheimer’s type dementia

HOW DONAMEM 5MG WORKS

DONAMEM5MG effectively controls the symptoms of dementia and Alzheimer’s disease by regulating the levels of certain chemical messengers (acetylcholine and glutamate) in the brain. Acetylcholine is a brain chemical which plays an important role in the functions of memory and cognition. Glutamate is another brain chemical that controls brain’s overall excitation. Overactivation of glutamate may cause damage to nerve cells. Alzheimer’s disease is usually characterized by decreased acetylcholine levels and increased glutamate levels in the brain.

DONAMEM 5MG contains two medicines, namely donepezil and memantine. Donepezil acts by restoring the levels of acetylcholine in the brain by blocking the actions of an enzyme called acetylcholinesterase which usually breaks down acetylcholine. Memantine acts by suppressing the overactivation of glutamate in the brain that causes nerve damage. Together, they restore the balance between chemical messengers in the brain, regulates proper transmission of nerve signals and reduces the symptoms of Alzheimer’s type dementia.

DIRECTIONS FOR USE

Take DONAMEM5MG as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. DONAMEM 5MG can be taken with or without food. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF DONAMEM 5MG

Diarrhea,Bruising (bleeding under the skin),Headache, dizziness,Nausea, vomiting,Loss of appetite,Increased weight,Loss of bladder control,Back pain,Drowsiness.

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